Synthesis, structure and biological activity of nickel(II) complexes of 5-methyl 2-furfural thiosemicarbazone a b c c - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of Inorganic Biochemistry Année : 2001

Synthesis, structure and biological activity of nickel(II) complexes of 5-methyl 2-furfural thiosemicarbazone a b c c

, , , , , (1) ,
1
Mostapha Jouad
  • Fonction : Auteur
Gerald Larcher
  • Fonction : Auteur
Magali Allain
Amedee Riou
  • Fonction : Auteur
Gilles M Bouet
  • Fonction : Auteur
  • PersonId : 1097390
Xuan Do
  • Fonction : Auteur

Résumé

5-Methyl 2-furfuraldehyde thiosemicarbazone (M5HFTSC) with nickel(II) leads to three types of complexes: [Ni(M5HFTSC) X ], 2 2 [Ni(M5FTSC) ] and [Ni(M5FTSC) ]?2DMF. In the first type the ligand remains in thione form, while in the two other, the anionic 2 2 thiolato form is involved. The species [Ni(M5HFTSC) X ] has been characterized spectroscopically. The structures of [Ni(M5FTSC) ]? 2 2 2 2DMF and [Ni(M5FTSC) ] have been solved using X-ray diffraction. Biological studies of [Ni(M5HFTSC) Cl ] have been carried out in 2 2 2 vitro for antifungal activity on human pathogenic fungi, Aspergillus fumigatus and Candida albicans, and in vivo for toxicity on mice. The results are compared to those of the ligand, the metal salt and a similar copper complex [Cu(M5HFTSC)Cl ].
Fichier principal
Vignette du fichier
2001-J Inorg Biochem-Mostapha.pdf (429.04 Ko) Télécharger le fichier
Origine : Accord explicite pour ce dépôt

Dates et versions

hal-03213408 , version 1 (05-05-2021)

Identifiants

Citer

Mostapha Jouad, Gerald Larcher, Magali Allain, Amedee Riou, Gilles M Bouet, et al.. Synthesis, structure and biological activity of nickel(II) complexes of 5-methyl 2-furfural thiosemicarbazone a b c c. Journal of Inorganic Biochemistry, 2001, 86, pp.565-571. ⟨10.1016/s0162-0134(01)00220-3⟩. ⟨hal-03213408⟩

Collections

UNIV-ANGERS
15 Consultations
111 Téléchargements

Altmetric

Partager

Gmail Facebook Twitter LinkedIn More