Increases in waist circumference and weight as predictors of type 2 diabetes in individuals with impaired fasting glucose: influence of baseline BMI: data from the DESIR study - Université d'Angers Accéder directement au contenu
Article Dans Une Revue Diabetes Care Année : 2010

Increases in waist circumference and weight as predictors of type 2 diabetes in individuals with impaired fasting glucose: influence of baseline BMI: data from the DESIR study

Résumé

Objective: To evaluate in impaired fasting glucose (IFG) the relative importance of increases in waist circumference and weight on progression to type 2 diabetes. Research design and methods: The 9-year incidence of diabetes was studied in 979 men and women with baseline IFG, from the Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort. Results: Increases in both waist circumference and weight were significantly associated with diabetes incidence. Standardized odds ratios (95% CI) were 1.79 (1.45-2.21) and 1.86 (1.51-2.30), respectively, after controlling for baseline risk factors. The impact of waist circumference increase was greater for BMI <25 kg/m(2) (2.40 [1.63-3.52]) than for BMI >or=25 kg/m(2) (1.66 [1.28-2.16]) and persisted after adjusting for concurrent changes in either insulinemia or the homeostasis model assessment of insulin resistance index. Weight change had a similar impact in both BMI groups. Conclusions: In individuals with IFG, it is important to monitor and prevent increases in waist circumference, in particular for those with BMI <25 kg/m(2).

Dates et versions

hal-03275657 , version 1 (07-07-2023)

Identifiants

Citer

Alain Gautier, Ronan Roussel, Pierre-Henri Ducluzeau-Fieloux, Céline Lange, Sylviane Vol, et al.. Increases in waist circumference and weight as predictors of type 2 diabetes in individuals with impaired fasting glucose: influence of baseline BMI: data from the DESIR study. Diabetes Care, 2010, 33 (8), pp.1850-1852. ⟨10.2337/dc10-0368⟩. ⟨hal-03275657⟩
31 Consultations
2 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More