<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-03247670</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-24T05:28:11+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="fr">New Use for a Compound as a Matrix in the Specific Detection, Identification and/or Quantification of Alkaloids by MALDI-TOF Mass Spectrometry</title>
            <author role="aut">
              <persName>
                <forename type="first">Marylène</forename>
                <surname>Dias</surname>
              </persName>
              <email type="md5">5d669ee52c0e133ff01b6e5a8469e107</email>
              <email type="domain">univ-angers.fr</email>
              <idno type="idhal" notation="string">marylene-dias</idno>
              <idno type="idhal" notation="numeric">736973</idno>
              <idno type="halauthorid" notation="string">1662-736973</idno>
              <affiliation ref="#struct-213131"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Eric</forename>
                <surname>Levillain</surname>
              </persName>
              <email type="md5">331530537320970cec956c3f348c1df3</email>
              <email type="domain">univ-angers.fr</email>
              <idno type="idhal" notation="string">eric-levillain</idno>
              <idno type="idhal" notation="numeric">178535</idno>
              <idno type="halauthorid" notation="string">25659-178535</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/N-8839-2015</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-5322-7434</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?hl=fr&amp;user=xBDSN7YAAAAJ&amp;view_op=list_works&amp;sortby=pubdate</idno>
              <idno type="IDREF">https://www.idref.fr/119139162</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/N-8839-2015</idno>
              <idno type="ORCID">https://orcid.org/0009-0006-4948-2620</idno>
              <affiliation ref="#struct-213131"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pascal</forename>
                <surname>Richomme</surname>
              </persName>
              <email type="md5">7f0c866101be6fd46b3f1fc6de4e11ee</email>
              <email type="domain">univ-angers.fr</email>
              <idno type="idhal" notation="numeric">1167080</idno>
              <idno type="halauthorid" notation="string">191503-1167080</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-7788-2556</idno>
              <idno type="IDREF">https://www.idref.fr/081099703</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=s_44VHEAAAAJ</idno>
              <idno type="VIAF">https://viaf.org/viaf/194958545</idno>
              <idno type="ISNI">http://isni.org/isni/0000000139157580</idno>
              <affiliation ref="#struct-84494"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Andreas</forename>
                <surname>Schinkovitz</surname>
              </persName>
              <email type="md5">c7b6c08c875e2f9102fce5f31b36c304</email>
              <email type="domain">univ-angers.fr</email>
              <idno type="idhal" notation="numeric">991938</idno>
              <idno type="halauthorid" notation="string">956905-991938</idno>
              <affiliation ref="#struct-84494"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Denis</forename>
                <surname>Seraphin</surname>
              </persName>
              <email type="md5">ff2a0e43e50352ecc7d244620a3ca981</email>
              <email type="domain">univ-angers.fr</email>
              <idno type="idhal" notation="numeric">964791</idno>
              <idno type="halauthorid" notation="string">895943-964791</idno>
              <affiliation ref="#struct-84494"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Okina</forename>
                <surname>Univ Angers</surname>
              </persName>
              <email type="md5">b5db9c104e451c4c3e7e86bba508166f</email>
              <email type="domain">contact.univ-angers.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2021-06-03 11:09:42</date>
              <date type="whenModified">2024-04-11 13:08:14</date>
              <date type="whenReleased">2021-06-03 11:09:42</date>
              <date type="whenProduced">2013</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="300611">
                <persName>
                  <forename>Okina</forename>
                  <surname>Univ Angers</surname>
                </persName>
                <email type="md5">b5db9c104e451c4c3e7e86bba508166f</email>
                <email type="domain">contact.univ-angers.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-03247670</idno>
            <idno type="halUri">https://univ-angers.hal.science/hal-03247670</idno>
            <idno type="halBibtex">dias:hal-03247670</idno>
            <idno type="halRefHtml">France, N° de brevet: Non spécifié. 2013</idno>
            <idno type="halRef">France, N° de brevet: Non spécifié. 2013</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-ANGERS">Université d'Angers</idno>
            <idno type="stamp" n="INC-CNRS">Institut de Chimie du CNRS</idno>
            <idno type="stamp" n="SONAS" corresp="UNIV-ANGERS">Substances d'Origine Naturelle et Analogues Structuraux</idno>
            <idno type="stamp" n="MOLTECH-ANJOU" corresp="UNIV-ANGERS">MOLTECH-Anjou</idno>
            <idno type="stamp" n="TEST2-HALCNRS">TEST2-HALCNRS</idno>
          </seriesStmt>
          <notesStmt/>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="fr">New Use for a Compound as a Matrix in the Specific Detection, Identification and/or Quantification of Alkaloids by MALDI-TOF Mass Spectrometry</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Marylène</forename>
                    <surname>Dias</surname>
                  </persName>
                  <email type="md5">5d669ee52c0e133ff01b6e5a8469e107</email>
                  <email type="domain">univ-angers.fr</email>
                  <idno type="idhal" notation="string">marylene-dias</idno>
                  <idno type="idhal" notation="numeric">736973</idno>
                  <idno type="halauthorid" notation="string">1662-736973</idno>
                  <affiliation ref="#struct-213131"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Eric</forename>
                    <surname>Levillain</surname>
                  </persName>
                  <email type="md5">331530537320970cec956c3f348c1df3</email>
                  <email type="domain">univ-angers.fr</email>
                  <idno type="idhal" notation="string">eric-levillain</idno>
                  <idno type="idhal" notation="numeric">178535</idno>
                  <idno type="halauthorid" notation="string">25659-178535</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/N-8839-2015</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-5322-7434</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?hl=fr&amp;user=xBDSN7YAAAAJ&amp;view_op=list_works&amp;sortby=pubdate</idno>
                  <idno type="IDREF">https://www.idref.fr/119139162</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/N-8839-2015</idno>
                  <idno type="ORCID">https://orcid.org/0009-0006-4948-2620</idno>
                  <affiliation ref="#struct-213131"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pascal</forename>
                    <surname>Richomme</surname>
                  </persName>
                  <email type="md5">7f0c866101be6fd46b3f1fc6de4e11ee</email>
                  <email type="domain">univ-angers.fr</email>
                  <idno type="idhal" notation="numeric">1167080</idno>
                  <idno type="halauthorid" notation="string">191503-1167080</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-7788-2556</idno>
                  <idno type="IDREF">https://www.idref.fr/081099703</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=s_44VHEAAAAJ</idno>
                  <idno type="VIAF">https://viaf.org/viaf/194958545</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000139157580</idno>
                  <affiliation ref="#struct-84494"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Andreas</forename>
                    <surname>Schinkovitz</surname>
                  </persName>
                  <email type="md5">c7b6c08c875e2f9102fce5f31b36c304</email>
                  <email type="domain">univ-angers.fr</email>
                  <idno type="idhal" notation="numeric">991938</idno>
                  <idno type="halauthorid" notation="string">956905-991938</idno>
                  <affiliation ref="#struct-84494"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Denis</forename>
                    <surname>Seraphin</surname>
                  </persName>
                  <email type="md5">ff2a0e43e50352ecc7d244620a3ca981</email>
                  <email type="domain">univ-angers.fr</email>
                  <idno type="idhal" notation="numeric">964791</idno>
                  <idno type="halauthorid" notation="string">895943-964791</idno>
                  <affiliation ref="#struct-84494"/>
                </author>
              </analytic>
              <monogr>
                <idno type="patentNumber">Non spécifié</idno>
                <country key="FR">France</country>
                <imprint>
                  <date type="datePub">2013</date>
                </imprint>
              </monogr>
              <idno type="okina">ua2348</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="fr">French</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="fr">Alkaloids</term>
                <term xml:lang="fr">MALDI-TOF MS</term>
                <term xml:lang="fr">Matrix</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="PATENT">Patents</classCode>
              <classCode scheme="halOldTypology" n="PATENT">Patents</classCode>
              <classCode scheme="halTreeTypology" n="PATENT">Patents</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>&lt;p&gt;The present invention relates to (i) a method of analysing small molecules that may have a mass of &amp;lt; 800 Da, in particular alkaloids, said method being generally referred to as MALDI-TOF-MS (or MALDI Time-of-Flight MAss Spectrometry) which is an acronym for a method of analysis by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry, to (ii) a molecule according to formula (I) and to the use thereof as a matrix in such an analysis method.&lt;/p&gt;</p>
            </abstract>
            <abstract xml:lang="fr">
              <p>&lt;p&gt;La présente invention se rapporte à (i) une méthode d'analyse de petites molécules pouvant avoir une masse &amp;lt; 800 Da, en particulier des alcaloïdes, ladite méthode étant généralement désignée sous le nom de MALDI-TOF-MS (ou spectrométrie de masse à temps de vol MALDI) qui est un acronyme pour méthode d'analyse par spectrométrie de masse à temps de vol à désorption/ionisation sous laser assistée par matrice, à (ii) une molécule de formule (I) et à son utilisation comme matrice dans une telle méthode d'analyse.&lt;/p&gt;</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-213131" status="VALID">
          <idno type="ISNI">0000000122880078</idno>
          <idno type="RNSR">200411667U</idno>
          <idno type="ROR">https://ror.org/039yyx623</idno>
          <orgName>MOLTECH-Anjou</orgName>
          <date type="start">2004-01-01</date>
          <desc>
            <address>
              <addrLine>MOLTECH-Anjou UMR 6200 CNRS - Université d'Angers, Faculté des Sciences, 2 Boulevard Lavoisier, Bâtiments K et Db - 49045 Angers CEDEX 01</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://moltech-anjou.univ-angers.fr/</ref>
          </desc>
          <listRelation>
            <relation name="UMR6200" active="#struct-74911" type="direct"/>
            <relation active="#struct-341038" type="direct"/>
            <relation name="UMR6200" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-84494" status="VALID">
          <idno type="IdRef">108015955</idno>
          <idno type="RNSR">199213267K</idno>
          <orgName>Substances d'Origine Naturelle et Analogues Structuraux</orgName>
          <orgName type="acronym">SONAS</orgName>
          <date type="start">1992-01-01</date>
          <desc>
            <address>
              <addrLine>Université d'Angers, SONAS - Campus du Végétal, 42 Rue Georges Morel - 49070 Beaucouzé</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://sonas.univ-angers.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-74911" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-74911" status="VALID">
          <idno type="IdRef">026402920</idno>
          <idno type="ISNI">0000000122483363</idno>
          <idno type="ROR">https://ror.org/04yrqp957</idno>
          <orgName>Université d'Angers</orgName>
          <orgName type="acronym">UA</orgName>
          <date type="start">1971-10-25</date>
          <desc>
            <address>
              <addrLine>Université d'Angers - 40 Rue de Rennes, BP 73532 - 49035 Angers CEDEX 01</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-angers.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-341038" status="VALID">
          <idno type="IdRef">232435103</idno>
          <idno type="ISNI">000000010626358X</idno>
          <idno type="ROR">https://ror.org/02cte4b68</idno>
          <orgName>Institut de Chimie - CNRS Chimie</orgName>
          <orgName type="acronym">INC-CNRS</orgName>
          <date type="start">2009-10-01</date>
          <desc>
            <address>
              <addrLine>CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 rue Michel-Ange75794 PARIS CEDEX 16 - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cnrs.fr/inc</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>