High-field quantitative transverse relaxation time, magnetization transfer and apparent water diffusion in experimental rat brain tumour - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue NMR in Biomedicine Année : 2000

High-field quantitative transverse relaxation time, magnetization transfer and apparent water diffusion in experimental rat brain tumour

High-field quantitative transverse relaxation time, magnetization transfer and apparent water diffusion in experimental rat brain tumour.

(1) , (1) , , , , ,
1
J Saint-Andre
  • Fonction : Auteur
V-G. Roullin
  • Fonction : Auteur
P. Jallet
  • Fonction : Auteur
J-J. Le Jeune
  • Fonction : Auteur
J. Saint-Andr�
  • Fonction : Auteur

Résumé

The potential of quantitative parameter images of transverse relaxation time T(2), apparent diffusion coefficient (ADC) and magnetization transfer ratio (MTR) to characterize experimental brain tumours was studied. Necrosis or haemorrhage can be detected using either MTR, ADC or T(2) (necrosis-MTR reduced by 35%, ADC and T(2) increased respectively by 170% and 100% compared with normal brain tissue; haemorrhage-MTR increased by 60%, ADC and T(2) decreased by 40% and 20%, respectively). Normal brain tissue can only be distinguished from tumour on T(2) and MTR parameter images. However, for small tumours (10 microl), the best contrast is observed with MTR, ca. 30%, whereas for T(2) the contrast is ca. 10%.

Dates et versions

hal-02374841 , version 1 (21-11-2019)

Identifiants

Citer

Laurent Lemaire, F. Franconi, J Saint-Andre, V-G. Roullin, P. Jallet, et al.. High-field quantitative transverse relaxation time, magnetization transfer and apparent water diffusion in experimental rat brain tumour. NMR in Biomedicine, 2000, 13 (3), pp.116-123. ⟨10.1002/1099-1492(200005)13:3<116::aid-nbm616>3.0.co;2-d⟩. ⟨hal-02374841⟩
13 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook Twitter LinkedIn More