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Article Dans Une Revue Microorganisms Année : 2018

The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis

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In recent years, the gut microbiota has been considered as a full-fledged actor of the gut-brain axis, making it possible to take a new step in understanding the pathophysiology of both neurological and psychiatric diseases. However, most of the studies have been devoted to gut bacterial microbiota, forgetting the non-negligible fungal flora. In this review, we expose how the role of the fungal component in the microbiota-gut-brain axis is legitimate, through its interactions with both the host, especially with the immune system, and the gut bacteria. We also discuss published data that already attest to a role of the mycobiome in the microbiota-gut-brain axis, and the impact of fungi on clinical and therapeutic research.
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hal-03164867 , version 1 (10-03-2021)

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R. Enaud, L. E. Vandenborght, N. Coron, T. Bazin, R. Prevel, et al.. The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis. Microorganisms, 2018, 6 (1), pp.22. ⟨10.3390/microorganisms6010022⟩. ⟨hal-03164867⟩

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