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HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy

Vincent Alcazer , Paola Bonaventura , Laurie Tonon , Emilie Michel , Virginie Mutez et al.
American Journal of Hematology, 2022, 97 (9), pp.1200-1214. ⟨10.1002/ajh.26647⟩
Journal articles hal-03784084v1

Direct T-cell Presentation by cDC1: The Key Feature for Cancer Vaccine Success?

Margaux Hubert , Christophe Caux , Jenny Valladeau-Guilemond
Cancer Immunology Research, 2022, 10 (8), pp.918-918. ⟨10.1158/2326-6066.CIR-22-0473⟩
Journal articles hal-03783998v1

Gene signature of circulating platelet‐bound neutrophils is associated with poor prognosis in cancer patients

Pacôme Lecot , Maude Ardin , Sébastien Dussurgey , Vincent Alcazer , Lyvia Moudombi et al.
International Journal of Cancer, 2022, 151 (1), pp.138-152. ⟨10.1002/ijc.33991⟩
Journal articles hal-03769720v1

Effect of acute aerobic exercise before immunotherapy and chemotherapy infusion in patients with metastatic non-small-cell lung cancer: protocol for the ERICA feasibility trial

Manon Gouez , Olivia Pérol , Maurice Pérol , Christophe Caux , Christine Ménétrier-Caux et al.
BMJ Open, 2022, 12 (4), pp.e056819. ⟨10.1136/bmjopen-2021-056819⟩
Journal articles hal-03769712v1

ZEB1 transcription factor promotes immune escape in melanoma

Maud Plaschka , Valentin Benboubker , Maxime Grimont , Justine Berthet , Laurie Tonon et al.
Journal for Immunotherapy of Cancer, 2022, 10 (3), pp.e003484. ⟨10.1136/jitc-2021-003484⟩
Journal articles hal-03769027v1

Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial

Jean-David Fumet , Emilie Lardenois , Isabelle Ray-Coquard , Philipp Harter , Florence Joly et al.
Cancers, 2022, 14 (5), pp.1189. ⟨10.3390/cancers14051189⟩
Journal articles hal-03769697v1
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Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy

Paola Bonaventura , Vincent Alcazer , Virginie Mutez , Laurie Tonon , Juliette Martin et al.
Science Advances , 2022, 8 (4), ⟨10.1126/sciadv.abj3671⟩
Journal articles hal-03552937v1

Les cellules CAR-T et les anticorps bispécifiques : un point sur ces avancées thérapeutiques majeures

Jacques-Olivier Bay , Christophe Caux
Bulletin du Cancer, 2021, 108 (10), pp.S1-S3. ⟨10.1016/j.bulcan.2021.11.006⟩
Journal articles hal-03769674v1
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Early changes in the immune microenvironment of oral potentially malignant disorders reveal an unexpected association of M2 macrophages with oral cancer free survival

Jebrane Bouaoud , Jean-Philippe Foy , Antonin Tortereau , Lucas Michon , Vincent Lavergne et al.
OncoImmunology, 2021, 10 (1), pp.1944554. ⟨10.1080/2162402x.2021.1944554⟩
Journal articles hal-03282364v1

Recruitment and Expansion of Tregs Cells in the Tumor Environment—How to Target Them?

Justine Cinier , Margaux Hubert , Laurie Besson , Anthony Di Roio , Céline Rodriguez et al.
Cancers, 2021, 13 (8), pp.1850. ⟨10.3390/cancers13081850⟩
Journal articles hal-03769664v1
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Neoadjuvant immune checkpoint inhibitors in cancer, current state of the art

Olivia Le Saux , Yasmine Lounici , Pauline Wajda , Sarah Barrin , Christophe Caux et al.
Critical Reviews in Oncology/Hematology, 2021, 157, pp.103172 -. ⟨10.1016/j.critrevonc.2020.103172⟩
Journal articles hal-03492630v1
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Type 1 conventional dendritic cells and interferons are required for spontaneous CD4 + and CD8 + T‐cell protective responses to breast cancer

Raphaël Mattiuz , Carine Brousse , Marc Ambrosini , Jean‐charles Cancel , Gilles Bessou et al.
Clinical and Translational Immunology, 2021, 10, ⟨10.1002/cti2.1305⟩
Journal articles hal-03329001v1
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Hepatitis B virus exploits C‐type lectin receptors to hijack cDC1s, cDC2s and pDCs

Laurissa Ouaguia , Tania Dufeu-Duchesne , Vincent Leroy , Thomas Decaens , Jean-Baptiste Reiser et al.
Clinical and Translational Immunology, 2020, 9 (12), pp.e1208. ⟨10.1002/cti2.1208⟩
Journal articles hal-03183870v1

Design and methods of a national, multicenter, randomized and controlled trial to assess the efficacy of a physical activity program to improve health-related quality of life and reduce fatigue in women with metastatic breast cancer: ABLE02 trial

Lidia Delrieu , Amélie Anota , Olivier Trédan , Damien Freyssenet , Aurélia Maire et al.
BMC Cancer, 2020, 20 (1), pp.622. ⟨10.1186/s12885-020-07093-9⟩
Journal articles hal-03769620v1

Expression of TAM-R in Human Immune Cells and Unique Regulatory Function of MerTK in IL-10 Production by Tolerogenic DC

Paul Giroud , Sarah Renaudineau , Laura Gudefin , Alexandre Calcei , Thierry Menguy et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.564133⟩
Journal articles hal-03769650v1
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Inflammasome Deletion Promotes Anti-tumor NK Cell Function in an IL-1/IL-18 Independent Way in Murine Invasive Breast Cancer

Baptiste Guey , Mélanie Bodnar-Wachtel , Annabelle Drouillard , Anaïs Eberhardt , Manon Pratviel et al.
Frontiers in Oncology, 2020, 10, ⟨10.3389/fonc.2020.01683⟩
Journal articles hal-03093037v1
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Durable and controlled depletion of neutrophils in mice

Gaël Boivin , Julien Faget , Pierre-Benoit Ancey , Aspasia Gkasti , Julie Mussard et al.
Nature Communications, 2020, 11 (1), pp.2762. ⟨10.1038/s41467-020-16596-9⟩
Journal articles inserm-02879178v1
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Les avancées actuelles de l’immunothérapie dans le cancer de l’ovaire

Olivia Le Saux , Bertrand Dubois , Marc-Henri Stern , Magali Terme , Eric Tartour et al.
Bulletin du Cancer, 2020, 107, pp.465 - 473. ⟨10.1016/j.bulcan.2019.11.015⟩
Journal articles hal-03490307v1
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IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer

Margaux Hubert , Elisa Gobbini , Coline Couillault , Thien-Phong Vu Manh , Anne-Claire Doffin et al.
Science Immunology, 2020, 5 (46), pp.eaav3942. ⟨10.1126/sciimmunol.aav3942⟩
Journal articles hal-02998632v1

CD163 + tumor‐associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes

Rodrigo Nalio Ramos , Céline Rodriguez , Margaux Hubert , Maude Ardin , Isabelle Treilleux et al.
Clinical and Translational Immunology, 2020, 9 (2), ⟨10.1002/cti2.1108⟩
Journal articles hal-03769582v1
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Les évolutions de la recherche en immuno-oncologie et leurs impacts sur la prise en charge des patients traités par immunothérapie

Christophe Caux
Bulletin du Cancer, 2020, 107, pp.6 - 9. ⟨10.1016/j.bulcan.2020.01.002⟩
Journal articles hal-03489582v1

Association between FGFR1 copy numbers, MAP3K1 mutations, and survival in axillary node-positive, hormone receptor-positive, and HER2-negative early breast cancer in the PACS04 and METABRIC studies

Dimitri Carene , Alicia Tran-Dien , Jérôme Lemonnier , Florence Dalenc , Christelle Levy et al.
Breast Cancer Research and Treatment, 2020, 179 (2), pp.387-401. ⟨10.1007/s10549-019-05462-y⟩
Journal articles hal-03769556v1

Repurposing infectious disease vaccines for intratumoral immunotherapy

Ignacio Melero , Maria Gato , Tala Shekarian , Angela Aznar , Sandrine Valsesia-Wittmann et al.
Journal for Immunotherapy of Cancer, 2019, 8 (1), pp.e000443. ⟨10.1136/jitc-2019-000443⟩
Journal articles hal-03769570v1
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La biologie des cibles PD-1 et CTLA-4 et la question des biomarqueurs

Marie-Caroline Dieu-Nosjean , Christophe Caux
médecine/sciences, 2019, 35 (12), pp.957-965. ⟨10.1051/medsci/2019192⟩
Journal articles hal-02463066v1

Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells

Beatris Mastelic-Gavillet , Blanca Navarro Rodrigo , Laure Décombaz , Haiping Wang , Giuseppe Ercolano et al.
Journal for Immunotherapy of Cancer, 2019, 7 (1), pp.257. ⟨10.1186/s40425-019-0719-5⟩
Journal articles hal-03769211v1

Lymphopenia in Cancer Patients and its Effects on Response to Immunotherapy: an opportunity for combination with Cytokines?

Christine Ménétrier-Caux , Isabelle Ray-Coquard , Jean-Yves Blay , Christophe Caux
Journal for Immunotherapy of Cancer, 2019, 7 (1), pp.85. ⟨10.1186/s40425-019-0549-5⟩
Journal articles hal-03769074v1
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Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection

Suzanne Faure-Dupuy , Marion Delphin , Ludovic Aillot , Laura Dimier , Fanny Lebossé et al.
Journal of Hepatology, 2019, 71 (6), pp.1086-1098. ⟨10.1016/j.jhep.2019.06.032⟩
Journal articles hal-03315737v1
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Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Nicolas Alcala , Noémie Leblay , Aurélie Gabriel , Lise Mangiante , Davis Hervás et al.
Nature Communications, 2019, 10 (1), pp.1-21. ⟨10.1038/s41467-019-11276-9⟩
Journal articles hal-02339242v1

Methotrexate Restores CD73 Expression on Th1.17 in Rheumatoid Arthritis and Psoriatic Arthritis Patients and May Contribute to Its Anti-Inflammatory Effect through Ado Production

Marion Bossennec , Céline Rodriguez , Margaux Hubert , Anthony Di-Roio , Christelle Machon et al.
Journal of Clinical Medicine, 2019, 8 (11), pp.1859. ⟨10.3390/jcm8111859⟩
Journal articles hal-03769215v1
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Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade

Tala Shekarian , Eva Sivado , Anne-Catherine Jallas , Stephane Depil , Janice Kielbassa et al.
Science Translational Medicine, 2019, 11 (515), pp.eaat5025. ⟨10.1126/scitranslmed.aat5025⟩
Journal articles hal-02347852v1